Venous thrombosis in oral contraceptive users and the presence of the JAK2 V617F mutation.
نویسندگان
چکیده
Elvira Grandone1, Donatella Colaizzo1, Giovanni L. Tiscia1, PatriziaVergura1, Elena Chinni2, Luigi Iannaccone3, Iole Antinolfi3, Maria A. Guardascione4, Maurizio Margaglione1,2 1Atherosclerosis and Thrombosis Unit, I.R.C. C.S. Casa Sollievo della Sofferenza, S. Giovanni R (FG) and 2Medical Genetics, University of Foggia, Foggia, Italy; 3Thrombosis and Haemostasis Centre, Cardarelli Hospital, Naples, Italy; 4Gastroenterology Department, Cardarelli Hospital, Naples, Italy
منابع مشابه
Evaluation of cerebral venous thrombosis risk following oral contraceptive use: A case report and update.
Background and Objectives: The aim of the present study was to report a case of cerebral venous thrombosis (CVT) folowing consumption of the oral contraceptive pills with high estrogen levels. Case Report: A 35-year-old woman presenting a headache was diagnosed with thrombosis in the upper sagittal, sigmoid and transverse veins, by CT SCAN, MRI and MRV of the brain. Conclusion: The chance ...
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The JAK2(V617F)mutation is recurrent in polycythemia vera and essential thrombocythemia, which are myeloproliferative neoplasms frequently associated with arterial and venous thromboembolism. It has also been reported as a marker for occult myeloproliferative disorder (MPD) in patients with splanchnic venous thrombosis. Limited data are available regarding the prevalence of the JAK2(V617F) muta...
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متن کاملIncidence of the JAK2 V617F mutation among patients with splanchnic or cerebral venous thrombosis and without overt chronic myeloproliferative disorders.
BACKGROUND Thrombosis of splanchnic or cerebral veins is a typical manifestation of polycythemia vera (PV) or essential thrombocythemia (ET). The recently identified Janus kinase 2 (JAK2) V617F somatic mutation is closely related to chronic myeloproliferative disorders (CMD). OBJECTIVE To assess the incidence of the JAK2 V617F mutation among patients with splanchnic or cerebral venous thrombo...
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ورودعنوان ژورنال:
- Thrombosis and haemostasis
دوره 99 3 شماره
صفحات -
تاریخ انتشار 2008